Heart medication side effects: What’s normal and what’s not

Medications can help people with coronary artery disease (CAD) live a healthy life. But they can also come with unwanted side effects. Here’s what you need to know to stay safe.

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Antiplatelet drugs 

What they do: Prevent blood clots. 

Examples: Aspirin (Bayer, Bufferin), clopidogrel (Plavix)  

Common side effects: Bruising, nosebleeds 

When to call your doctor: If you notice dark red or black stool or if you vomit blood, these may be signs of internal bleeding. It’s a rare side effect that can be life threatening if left untreated. 

Statins 

What they do: Reduce cholesterol. 

Examples: Atorvastatin (Lipitor), lovastatin (Altoprev) 

Common side effects: Muscle pain, weakness, slight rise in blood sugar  

When to call your doctor: Severe muscle cramps or red urine may signal rhabdomyolysis, a rare complication where muscle tissue breaks down. Dark urine and yellow eyes and skin may also be signs of liver damage. 

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Beta blockers 

What they do: Slow your heart rate and lower your blood pressure. 

Examples: Metoprolol (Lopressor) or propranolol (Inderal LA) 

Common side effects: Fatigue, decreased libido 

When to call your doctor: If you experience shortness of breath, chest pain, or dizziness, your doctor may lower your dose or switch you to another medication, like a calcium channel blocker.